Stop smoking
Zyban (Bupropion) , BestDrugsNow.com - online pharmacy.
Generic Zyban (Bupropion) 150 mg
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| $65.09($2.17 per pill) | 30 pills |
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| $115.63($1.93 per pill) | 60 pills |
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| $157.68($1.75 per pill) | 90 pills |
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Product Description
Zyban (Bupropion)
DRUG CLASS AND MECHANISM : Bupropion is in a an class of drugs called antidepressant medications. They act on chemicals within the brain that nerves use to send messages to each other. These chemical messengers are called neurotransmitters. Neurotransmitters are produced by nerve cells and are released by the cells. The neurotransmitters move to nearby nerve cells and affect on the cells activity. It is believed by many experts that a disbalance in these neurotransmitters causes depression. Bupropion isn't similar to other antidepressants. It acts by blocking the reuptake of dopamine, serotonin, and norepinephrine. It results in more dopamine, serotonin, and norepinephrine to transmit messages to other nerves. Bupropion is a unique medication. Its major effect is on dopamine, an effect which is not shared by the selective serotonin reuptake inhibitors or SSRIs (e.g. paroxetine, Paxil; fluoxetine, Prozac; sertraline, Zoloft) or the tricyclic antidepressants or TCAs (e.g. amitriptyline, Elavil; imipramine, Tofranil; desipramine, Norpramin).
GENERIC AVAILABLE : YES.
PRESCRIPTION : YES.
PREPARATIONS : Wellbutrin, round tablets: 75 mg (orange), 100mg (red). Zyban, round tablets: 100 mg (blue),
150 mg (purple). Wellbutrin SR, round tablets: 100 mg (blue), 150 mg (purple). Wellbutrin XL, tablets: 150 and 300 mg.
STORAGE : Tablets should be stored at room temperature, 15- 25°C (59-77°F).
PRESCRIBED FOR : Wellbutrin, Wellbutrin SR, and Wellbutrin XL are applied for the treatment of major depression
and seasonal affective disorder (depression that appears primarily during the fall and winter). Zyban has been approved as a help
to patients who want to stop smoking.
DOSING : upropion usually is accepted in two or three doses during the day. In case of prescription for stop smoking, bupropion usually is started as 150 mg once a day for three days, and then the dose is extended if the patient tolerates the starting dose. Smoking is usually stopped in two weeks after starting bupropion therapy. Wellbutrin SR is appointed as two daily doses. Wellbutrin XL is appointed as one dose daily.
DRUG INTERACTIONS : Although there have been no systematic studies about the potential interaction of bupropion with other medicines, this drug should be applied cautiously in patients comsuming medicines that decrease the threshold for seizures. Such drugs include prochlorperazine (Compazine), chlorpromazine (Thorazine), and other antipsychotic medications of the phenothiazine class. Additionally, persons who are withdrawing from benzodiazepines (e.g. diazepam, Valium; alprazolam, Xanax) have an extended risk for seizures.
PREGNANCY : There have been no adequate studies of bupropion in pregnant women. Studies in pregnant animals using doses much higher than those applied in humans, have shown that bupropion is safe. That's why bupropion can be appointed in pregnant women if the physician feels that it is necessary.
NURSING MOTHERS : It is unknown if bupropion has secretion to the breast milk.
SIDE EFFECTS : The most common side effects of bupropion include agitation, dry mouth, insomnia, headache, nausea, constipation, and tremor. Some people can notice the agitation or insomnia after starting therapy. Some patients may experience weight loss. In rare cases patients may experience manic episodes or hallucinations. Four of every 1000 persons who consume bupropion in doses less than 450 mg/day experience seizures. When doses exceed 450 mg/day, the risk extends ten-fold. Other risk factors for seizures are past injury to the head and drugs which can decrease the threshold for seizures. (See drug interactions.) "If antidepressants are discontinued abruptly, symptoms may occur such as dizziness, headache, nausea, changes in mood, or changes in the sense of smell, taste, etc. (Such symptoms even may occur when even a few doses of antidepressant are missed.) Therefore, it is recommended that the dose of antidepressant be reduced gradually when therapy is discontinued." It has been supposed that bupropion and SSRIs may cause worsening of depression and even lead to suicide in a small number of patients. It is difficult to apprise these potential side effects in depressed patients because depression can progress with or without treatment, and suicide is an independent continuation of depression. Moreover, there are not enough certificates for the benefit of these potential by-effects. Therefore, no conclusions can yet be rejected about the relationship between bupropion and SSRIs and worsening depression and suicide. Until better information is available, patients consuming bupropion or SSRIs should be monitored for worsening depression and suicidal tendencies.
