There is a chemical parameter of blood which can prevent serious allergic reactions - anaphylaxis, caused such food to products as a peanut, medicines and poison of an insect. New research shows, that it for a chemical parameter and why levels differ at different people. Approximately 2000 Americans die every year in result anaphylaxis.
Approximately 40000 person in the USA every year have anaphylaxis reaction, from approximately 12 million who suffers from some allergy of the foodstuffs. This studying the first to show, that there is a communication between anaphylaxis and a chemical parameter in blood. In this studying scientists wanted to supervise levels (the factor making active a plate) in 67 participants - 42 has transferred at least one episode anaphylaxis while others 25 had no (healthy participants). Animals in their blood have been connected to high levels of a parameter with anaphylaxis in the previous studying.
Researchers wanted find out, whether levels in people also could be connected to an allergy. They also have measured a level of participants acetylhydrolase. A level acetylhydrolase - enzyme which breaks immune reaction as soon as it gets in a body. Patients who have transferred incident anaphylaxis, have been divided into groups, depending on gravity of their reactions. Researchers inform, that 6 % of their healthy participants (group of the control) have lifted levels of a parameter, in comparison with 22 % of participants anaphylaxis which have tested insignificant attributes, and 100 % from those who has tested serious reactions.
Participants who have tested the worse reactions anaphylaxis also, had the lowest levels acetylhydrolase - in other words, they had the lowest levels of enzyme which breaks a level, they were least capable to operate levels of a parameter. Article informs, that in separate studying, there were ten children who have died in result anaphylaxis to peanuts also, had considerably low levels of enzyme.
Researchers believe, that this studying can follow finally ahead to developing methods to predict, who - most of all because of danger of transition moderate to serious anaphylaxis, and also creation of treatment by some, such as therapy of replacement of enzyme.
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