Diabetes
BestDrugsNow.com - online pharmacy, brand medications, Avandia (Rosiglitazone maleate).
Generic
Avandia (Rosiglitazone maleate) 4 mg
Price |
Quantity |
Saving |
Buy NOW |
|||
| $54.58($1.82 per pill) | 30 pills |
N/A | ||||
| $90.66($1.51 per pill) | 60 pills |
$19.00 | ||||
| $109.71($1.22 per pill) | 90 pills |
$54.00 | ||||
Generic
Avandia (Rosiglitazone maleate) 2 mg
Price |
Quantity |
Saving |
Buy NOW |
|||
| $59.80($1.00 per pill) | 60 pills |
N/A | ||||
| $80.18($0.98 per pill) | 90 pills |
$10.00 | ||||
Generic Avandia (Rosiglitazone maleate) 8 mg
Price |
Quantity |
Saving |
Buy NOW |
|||
| $94.91($3.16 per pill) | 30 pills |
N/A | ||||
| $157.67($2.63 per pill) | 60 pills |
$32.00 | ||||
| $190.80($2.12 per pill) | 90 pills |
$94.00 | ||||
Product Description
Avandia (Rosiglitazone maleate)
DRUG CLASS AND MECHANISM : Rosiglitazone is a madicine that should be accepted orally. This drug decreases the quantity of sugar (glucose) in the blood. It is applied for treating patients with type 2 diabetes and concerns to a class of anti-diabetic drugs called thiazolidinediones. Another drud of this class is pioglitazone (Actos). Insulin is a hormone produced by the pancreas. Insulin supervises the levels of glucose in the blood. Insulin stimulates the cells of the body to grasp glucose from the blood and thereby lowers the level of glucose in the blood. Patients with type II diabetes can't produce enough insulin, that's why the cells in their bodies can't grasp enough glucose from the blood, and the level of glucose extends. Rosiglitazone is often conserns to an "insulin sensitizer" because it operates to the insulin receptors on cells and makes cells more sensitive (more responsive) to insulin. It leads to better grasp of glucose from the blood. But some insulin must be produced by the pancreas for the work of rosiglitazone. Rosiglitazone was approved by the FDA on May 28, 1999.
GENERIC AVAILABLE : No.
PRESCRIPTION : YES.
PREPARATIONS : Tablets: 2, 4, and 8 mg.
STORAGE : Tablets should be stored at room temperature, 15-30°C (59-86°F).
PRESCRIBED FOR : Rosiglitazone is applied for treatment type II diabetes. But it should be used in combinstion with diet, exercise, weight control and cessation of smoking. Rosiglitazone may be accepted alone or combined with other types of anti-diabetic medicine such as metformin or sulfonylureas as well as insulin. As naturally-secreted insulin is nessesary for the usage of rosiglitazone thow it is not recommended for acception in type I diabetes where the quantity of insulin is very low or absent.
DOSING : Rosiglitazone may be accepted once or twice a day, with food or without it. Daily doses range from 4 to 8 mg in combination with other antidiabetic medications or without them. Ther are no dditional effects in case of usage more than 8mg daily.
DRUG INTERACTIONS : Rifampin reduces the blood concentration of rosiglitazone by extending its destruction in the liver. That's why, the usage of rifampin may diminish the effect of rosiglitazone. Gemfibrozil extends the concentration of rosiglitazone in the blood by decreasing its destruction. Therefore, rosiglitazone can extend the side effects of rosiglitazone.
PREGNANCY : There are no adequate studies about rosiglitazone's influence in pregnant women.
NURSING MOTHERS : It is unknown if rosiglitazone is secreted in breast milk. Therefore, the safety of rosiglitazone to nursing infants also is unknown.
SIDE EFFECTS AND PRECAUTIONS : Rosiglitazone alone or in combination with metformin may lead to upper respiratory tract infection, headache, back pain, hyperglycemia, fatigue, sinusitis, diarrhea, and hypoglycemia. It has been shown that rosiglitazone can lead to moderate accumulation of fluid (edema) and heart failure. Anemia is another side effect. Rosiglitazone also causes extending uantity of weight gain with increasing doses. Since troglitazone, a related drug, was associated with liver injury, liver tests are recommended to be done before the beginning of therapy and periodically thereafter. Side effects which may appear during the treatment include unexplained nausea, vomiting, abdominal pain, fatigue, anorexia (loss of appetite), or dark urine. This medicine may increase probability of pregnancy by resuming ovulation in premenopausal women who have not been ovulating because they are resistant to insulin. Rosiglitazone may improve insulin sensitivity and lead to ovulation and pregnancy. Studies testing rosiglitazone excluded New York Heart Association Class III and IV patients with the most serious heart disease. Therefore, it is unknown how these classes of patients will react to treatment because of the fluid accumulation that may lead to heart failure in these patients. Rosiglitazone alone or in combination with metformin has showed different effects on blood lipids. Durind the studies acception of rosiglitazone has shown elevated total and low-density cholesterol (LDL) levels within the first two months of therapy with or without metformin, while high-density cholesterol (HDL) levels increase and free fatty acids reduse with continued therapy.
