Blood pressure pills
Avapro (Irbesartan), BestDrugsNow.com - online pharmacy.
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Product Description
Avapro (Irbesartan)
DRUG CLASS AND MECHANISM : Irbesartan belongs to class of medicines called angiotensin receptor blockers. This group also includes such drugs as losartan (Cozaar) and valsartan (Diovan). This medicines block angiotensin II, a chemical that narrows the arteries and veins. This action leads to dilation of the arteries and veins, and blood pressure is decreased. When the blood pressure is lowered, the heart doesn't have to work so hard for pumping blood. Irbesartan was approved by the FDA in 1998.
GENERIC AVAILABLE : No.
PRESCRIPTION : YES.
PREPARATIONS : Tablets: 75mg, 150mg, 300mg.
STORAGE : Tablets should be kept at room temperature, 15-30°C (59-86°F).
PRESCRIBED FOR : Irbesartan is applied for treatment of high blood pressure. It may be used alone or in combination with other drugs. This medicin has less effect in black patients. The effect that is similar to another class of drugs accepted for the treatment of high blood pressure called ACE inhibitors--captopril (Capoten), enalapril (Vasotec), benazepril (Lotensin), and lisinopril (Zestril). There have been carried out studied about Irbesartan in patients with congestive heart failure to determine if its blood pressure-lowering effects are advantageously to the heart.
DOSING : Irbesartan usually is taken once a day.
DRUG INTERACTIONS : Threr were no reports about important drug interactions with irbesartan. Since angiotensin receptor blockers such as irbesartan can extend potassium's concentration in blood, other drugs that also increase the concentration of potassium, such as hydrochlorothiazide (Dyazide) and spironolactone (Aldactone), as well as potassium additions, should be applied with irbesartan very cautiously.
PREGNANCY : Medicines that work like irbesartan--specifically, ACE inhibitors such as enalapril (Vasotec)--can cause injury and even laed to death of the fetus. Because of the possibility of having a similar effect on the fetus irbesartan shouldn't be accepted during pregnancy.
NURSING MOTHERS : It is reported that another angiotensin receptor blocker, losartan (Cozaar), is secreted in rat milk and is toxic to newborn rats. Since irbesartan is similar to losartan and may share a similar effect, irbesartan shouldn't be given to nursing mothers. There are no reports about safety and efficacy of irbesartan in children.
SIDE EFFECTS : The most common side effects with irbesartan are diarrhea (occurring in 1 in 30 persons) and abdominal pain or heartburn (occurring in 1 in 50 persons).
