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Generic Singulair (Montelukast)

 

 

 

 

Generic Singulair (Montelukast) 4 mg pills

Montelukast is an oral leukotriene receptor antagonist applied for treating asthma and seasonal allergic rhinitis (hay fever). Leukotrienes are a group of naturally appeared chemicals in the body that provoke inflammation in asthma and seasonal allergic rhinitis and in other diseases where inflammation is important (such as allergy). They are formed by cells, released, and then bound to other cells, and this stimulates the cells to strengthen inflammation. The mechanism of action of montelukast is similar to zafirlukast (Accolate). It ihibits the binding of some leukotrienes. Unlike zafirlukast, montelukast doesn't block CYP2C9 or CYP3A4, two enzymes in the liver that are necessary for destructing and eliminating many drugs. Therefore, unlike zafirlukast, montelukast is not expected to affect the elimination of other drugs. The safety and effectiveness of montelukast has been shown in children as young as 6 months of age. It was approved by the FDA in 1998....


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